EMBRYO-DESTROYING EFFECT OF INJECTED PHENOBARBITAL IN THE MOUSE
- 1 January 1964
- journal article
- research article
- Published by S. Karger AG in Cells Tissues Organs
- Vol. 58 (3), 217-221
- https://doi.org/10.1159/000142584
Abstract
Pregnant NMRI mice, injected with phenobarbital showed a high fetal loss. This effect was stronger the earlier the injections were begun during pregnancy and the higher the dosage. No malformations were encountered. The danger of judging teratogenicity of a drug from experiments showing fetal wastage is stressed.Keywords
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- Possible role of histamine in rat pregnancyThe Journal of Physiology, 1962
- ALCOHOL AND EYE DEFECTSJournal of Heredity, 1927