A FURTHER STUDY OF THE CROSS REACTION BETWEEN THE SPECIFIC POLYSACCHARIDES OF TYPES III AND VIII PNEUMOCOCCI IN HORSE ANTISERA
Open Access
- 1 January 1942
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 75 (1), 35-47
- https://doi.org/10.1084/jem.75.1.35
Abstract
1. The cross reaction of the specific polysaccharide of Type VIII pneumococcus with Type III antipneumococcus horse serum has been studied quantitatively and found similar to the S III-anti-S VIII reaction. 2. Contrasted with the general similarity of the two-segment reaction curves were distinct qualitative and quantitative differences in the course and character of the reciprocal reactions with respect to each segment. 3. These differences could be interpreted in terms of the known chemical differences between the specific polysaccharides of the two types. A minimum molecular weight of 62,000 was calculated for S III and 140,000 for S VIII. 4. It was also found possible to fractionate the Type VIII antibody into portions characteristic of each segment of the cross reaction curve. At least three different kinds of Type III and Type VIII anticarbohydrates were identified.This publication has 16 references indexed in Scilit:
- PROPERTIES OF THE TYPE SPECIFIC PROTEINS OF ANTIPNEUMOCOCCUS SERAThe Journal of Experimental Medicine, 1937
- A QUANTITATIVE STUDY OF THE CROSS REACTION OF TYPES III AND VIII PNEUMOCOCCI IN HORSE AND RABBIT ANTISERAThe Journal of Experimental Medicine, 1937
- THE SPECIFIC POLYSACCHARIDES OF TYPES I, II, AND III PNEUMOCOCCUSThe Journal of Experimental Medicine, 1936
- A QUANTITATIVE THEORY OF THE PRECIPITIN REACTIONThe Journal of Experimental Medicine, 1935
- THE PRECIPITIN REACTION BETWEEN TYPE III PNEUMOCOCCUS POLYSACCHARIDE AND HOMOLOGOUS ANTIBODYThe Journal of Experimental Medicine, 1935
- CHEMO-IMMUNOLOGICAL STUDIES ON CONJUGATED CARBOHYDRATE-PROTEINSThe Journal of Experimental Medicine, 1934
- STUDIES ON THE PRECIPITIN REACTIONThe Journal of Experimental Medicine, 1933
- QUANTITATIVE STUDIES ON THE PRECIPITIN REACTIONThe Journal of Experimental Medicine, 1932
- A QUANTITATIVE STUDY OF THE PRECIPITIN REACTION BETWEEN TYPE III PNEUMOCOCCUS POLYSACCHARIDE AND PURIFIED HOMOLOGOUS ANTIBODYThe Journal of Experimental Medicine, 1929
- CHEMO-IMMUNOLOGICAL STUDIES ON CONJUGATED CARBOHYDRATE-PROTEINSThe Journal of Experimental Medicine, 1929