Hydroxy group directed hydrogenation with rhodium and iridium catalysts. Synthesis of a protected chiral carbocyclic analogue of daunosamine

Abstract

Hydroxy group directed homogeneous alkene hydrogenation, with transition metal complexes of an appropriate mthylenecyclohexane derivative prepared from D-glucose proceeded stereospecifically from the more hindered side and allowed a chiral protected carbocyclic analogue of daunosamine to be prepared.