Long term follow-up of dermatitis herpetiformis with and without dietary gluten withdrawal
- 1 December 1982
- journal article
- research article
- Published by Oxford University Press (OUP) in British Journal of Dermatology
- Vol. 107 (6), 631-640
- https://doi.org/10.1111/j.1365-2133.1982.tb00520.x
Abstract
Seventy-eight patients with dermatitis herpetiformis have been followed up for periods ranging from 3 to 14 years (mean 7.4). Forty-two patients were treated with gluten-free diet (GFD) and thirty-six took a normal diet (ND). Thirty of the forty-two (71%) taking the GFD were able to discontinue drugs previously needed to control their rash compared with five (14%) of the thirty-six patients taking a ND. The mean time taken to reduce drug requirements for patients taking a GFD was 8 months (range 4–30), and for stopping drugs, 29 months (range 6–108). The incidence of macroscopic abnormality of the small intestine decreased from 69 to 15%, and the mean intra-epithelial lymphocyte count decreased significantly in those patients taking a GFD, whereas there was no significant change in patients taking a ND. The improvement in the skin and intestinal lesions was related to the strictness of the GFD.This publication has 14 references indexed in Scilit:
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