A Preliminary Comparison of Lidocaine and Xylazine as Epidural Analgesics in Ponies
- 1 January 1989
- journal article
- research article
- Published by Wiley in Veterinary Surgery
- Vol. 18 (1), 85-86
- https://doi.org/10.1111/j.1532-950x.1989.tb01046.x
Abstract
Xylazine (0.35 mg/kg) or lidocaine (0.35 mg/kg) was injected into the epidural space of six ponies to compare their effectiveness as epidural analgesics. Each pony received both treatments at 1 week intervals with the order of treatments randomized. Xylazine produced analgesia of significantly longer duration (247 +/- 58 minutes) than that produced by an equal dose of lidocaine (135 +/- 22 minutes). Mild transient ataxia of no clinical significance developed in all ponies with both treatments. Spinal cords were removed from two ponies and examined histologically. No discernible pathologic changes were noted.Keywords
This publication has 5 references indexed in Scilit:
- Epidural Clonidine Produces Antinociception, But Not Hypotension, In SheepAnesthesiology, 1987
- Pharmacological characterization and regional distribution of α-noradrenergic binding sites of rat spinal cordEuropean Journal of Pharmacology, 1985
- Intrathecal Morphine ToleranceAnesthesiology, 1985
- Distribution of α2 agonist binding sites in the rat and human central nervous system: Analysis of some functional, anatomic correlates of the pharmacologic effects of clonidine and related adrenergic agentsBrain Research Reviews, 1984
- α Agonist and Local anaesthetic properties of XylazineZentralblatt für Veterinärmedizin Reihe A, 1978