Local Clearance of 131I-4-Iodoantipyrine in Oral Mucosa and Subcutaneous Tissue of Cats

Abstract

¹³¹I-4-iodoantipyrine clearances from injection sites in oral submucosa were at least twice as rapid as clearances in subcutaneous tissue in cats. There was a positive correlation between the rapidity of clearances in the two tissues. Epinephrine, a vasoconstrictor, depressed clearances in both tissues, whereas papaverine, a vasodilator, increased clearances.