Hydroxylation of dehydroepiandrosterone in human scalp hair folhcles
- 1 June 1979
- journal article
- research article
- Published by Wiley in British Journal of Dermatology
- Vol. 100 (6), 693
- https://doi.org/10.1111/j.1365-2133.1979.tb08074.x
Abstract
The dehydroepiandrosterone hydroxylating enzyme system in the [human] hair follicle was characterized. It is found in the particulate fraction of the follicle, and is inhibited by CO and the cytochrome P450 inhibitor, metyrapone and appears to be dependent upon NADPH. In these major characteristics the hair follicle enzyme is very similar to the liver monooxygenase system.This publication has 7 references indexed in Scilit:
- Fabry's disease: biochemical and histochemical studies on hair roots for carrier detectionBritish Journal of Dermatology, 1978
- Enzymes of galactose metabolism in human hair rootsBritish Journal of Dermatology, 1977
- Fabry's disease: Heterozygote detection by hair root analysisHuman Genetics, 1976
- Studies on hair roots for carrier detection in hypoxanthine‐guanine phosphoribosyl transferase deficiencyClinical Genetics, 1974
- The Metabolism of Dehydroepiandrosterone by Human Scalp Hair FolliclesJournal of Clinical Endocrinology & Metabolism, 1973
- Metabolism of androgens by isolated human beard hair folliclesSteroids, 1971
- Lesch-Nyhan Syndrome: Rapid Detection of Heterozygotes by Use of Hair FolliclesScience, 1971