Binding of (T,G)‐A—L by normal sera

Abstract

The synthetic polypeptide poly‐L‐(Tyr, Glu)‐poly‐DL‐Ala—poly‐L‐Lys [(T,G)‐A—L] was found to be bound not only by mouse immune serum, but also by nonimmune sera from several species. A combination of immunoelectrophoresis and autoradiography showed that albumin, β‐globulins and immunoglobulins in these sera maybind the antigen. This binding pattern is different, however, for the various species investigated.