The Use of Apolipoprotein CII as a Genetic Marker for Myotonic Dystrophy
- 1 March 1987
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Neurology
- Vol. 44 (3), 273-275
- https://doi.org/10.1001/archneur.1987.00520150029015
Abstract
• In five families we have confirmed the close linkage between the genes for myotonic dystrophy and apolipoprotein Cll. The total maximum lod (log of the odds) score was 3.32 at 0 recombination. We demonstrate that the use of a Ban I restriction site polymorphism for apolipoprotein Cll adds additional useful information when combined with the more commonly used Taq I polymorphism. The potential practical clinical use of these markers for the prenatal diagnosis of myotonic dystrophy is demonstrated.This publication has 10 references indexed in Scilit:
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