SPECT Quantification of Technetium-99m Microspheres Within the Canine Lung
- 31 December 1984
- journal article
- research article
- Published by Wolters Kluwer Health in Journal of Computer Assisted Tomography
- Vol. 9 (1), 73-77
- https://doi.org/10.1097/00004728-198501000-00015
Abstract
Surgicalttenuation compensated single photon emission CT (SPECT) count rates of 99mTc microsphere activities from 151 selected small regions of interest (ROIs) in an intact canine thorax were compared with the count rates obtained from scintillation camera images of similar ROIs from frozen slices of the thorax. A first-order method was used to compensate the SPECT and scintillation camera images for the effect of Compton scattering. The SPECT and scintillation camera count rates correlated well: r = 0.95 (RMS error 4.8 counts/s) for 19 X 19 X 13 mm thick ROls. We conclude that regional quantification of 99mTc microspheres within the dog thorax is possible using camera-based SPECT systems.Keywords
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