Effect of corticotropin (ACTH) on experimental seizures
- 1 December 1965
- journal article
- research article
- Published by Wolters Kluwer Health in Neurology
- Vol. 15 (12), 1136
- https://doi.org/10.1212/wnl.15.12.1136
Abstract
ACTH caused a significant reduction in the threshold to minimal clonic electroshock seizures in young rats. The reduction in seizure threshold was correlated with an increase in the concentration of intracellular Na in the brain. The effects of ACTH on the seizure threshold and intracellular brain Na were independent of the stimulation of the adrenal glands.This publication has 15 references indexed in Scilit:
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