A survey of herbicides for their effect upon protein synthesis.

Abstract

Leucine-1-C14 was administered to coleoptile segments of barley and to stem segments of Sesbania exaltata (a legume), and the rate of protein synthesis was measured. Twenty-three herbicides were tested to determine if they affected protein synthesis. Five herbicides depressed protein synthesis. In 2 cases (pentachlorophenol and 3,5-diiodo-4-hydroxybenzonitrile) uptake of [alpha] -amino-n-butyric acid also was inhibited. But amino acid incorporation into protein, as well as uptake, was inhibited by isopropyl-N-(3-chlorophenyl)-carbamate (CIPC), by 2-chloro-N,N-diallylacetamide (CDAA), and by disodium 3,6-endoxohexahydrophthalate (endothal).