GeneMANIA Cytoscape plugin: fast gene function predictions on the desktop
Top Cited Papers
Open Access
- 5 October 2010
- journal article
- research article
- Published by Oxford University Press (OUP) in Bioinformatics
- Vol. 26 (22), 2927-2928
- https://doi.org/10.1093/bioinformatics/btq562
Abstract
Summary: The GeneMANIA Cytoscape plugin brings fast gene function prediction capabilities to the desktop. GeneMANIA identifies the most related genes to a query gene set using a guilt-by-association approach. The plugin uses over 800 networks from six organisms and each related gene is traceable to the source network used to make the prediction. Users may add their own interaction networks and expression profile data to complement or override the default data. Availability and Implementation: The GeneMANIA Cytoscape plugin is implemented in Java and is freely available at http://www.genemania.org/plugin/. Contact:gary.bader@utoronto.ca; quaid.morris@utoronto.caKeywords
This publication has 9 references indexed in Scilit:
- The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene functionNucleic Acids Research, 2010
- Fast integration of heterogeneous data sources for predicting gene function with limited annotationBioinformatics, 2010
- A Compendium of Potential Biomarkers of Pancreatic CancerPLoS Medicine, 2009
- NCBI GEO: archive for high-throughput functional genomic dataNucleic Acids Research, 2009
- GeneMANIA: a real-time multiple association network integration algorithm for predicting gene functionGenome Biology, 2008
- A critical assessment of Mus musculusgene function prediction using integrated genomic evidenceGenome Biology, 2008
- The BioGRID Interaction Database: 2008 updateNucleic Acids Research, 2007
- Online Predicted Human Interaction DatabaseBioinformatics, 2005
- Cytoscape: A Software Environment for Integrated Models of Biomolecular Interaction NetworksGenome Research, 2003