Prognostic factors of esophageal carcinoma: Univariate and multivariate analyses
- 1 February 1986
- journal article
- research article
- Published by Wiley in Journal of Surgical Oncology
- Vol. 31 (2), 108-112
- https://doi.org/10.1002/jso.2930310207
Abstract
The correlation of 5‐year survival rate with various clinical and histopath‐ological factors was studied using univariate and multiple analyses of 128 patients who had undergone resection for esophageal carcinoma between 1965 and 1978 in the Department of Surgery, Kyushu University Hospital. The depth of penetration, lymph node metastasis, lymphatic or vascular invasion, and INF had a significant correlation with 5‐year survival in the univariate analysis; however, only depth of penetration and lymph node metastasis were prognostic factors with a significant difference, in the multivariate analysis. In 55 patients in whom the cell nuclear DNA content had been determined, the DNA pattern was the greatest prognostic factor (p < 0.01), in multivariate analyses. We propose that the DNA distribution in the malignant cells should be examined as a most pertinent prognostic factor.Keywords
This publication has 8 references indexed in Scilit:
- Cytophotometric dna analysis of mucosal and submucosal carcinoma of the esophagusCancer, 1984
- EsophagogastrectomyAnnals of Surgery, 1983
- Differentiation of growth patterns of early gastric carcinoma determined by cytophotometric0 DNA analysisCancer, 1983
- Carcinoma of the EsophagusAnnals of Surgery, 1982
- A safer and more reliable operative technique for esophageal reconstruction using a gastric tubeThe American Journal of Surgery, 1980
- Follow‐up results after resection of thoracic esophageal carcinomaWorld Journal of Surgery, 1978
- Guide lines for the clinical and pathologic studies on carcinoma of the esophagusSurgery Today, 1976
- On the prediction of phenomena from qualitative data and the quantification of qualitative data from the mathematico-statistical point of viewAnnals of the Institute of Statistical Mathematics, 1951