Delayed Recovery of Function following Orbital Prefrontal Lesions in Infant Monkeys

Abstract
Monkeys given orbital prefrontal lesions at 1, 4, or 8 weeks of age exhibited a severe learning disability when they were tested at 1 year of age, but showed substantial recovery by the time they were 2 years old. These results suggest that the protracted maturation of intact cortical regions is important in recovery of function after early brain injury.