EVIDENCE FOR THE EXISTENCE OF FOUR TYPES OF RIBONUCLEOPROTEIN IN THE NERVE CELLS OF THE CEREBELLUM IN THE ADULT CAT
- 1 March 1965
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Zoology
- Vol. 43 (2), 357-367
- https://doi.org/10.1139/z65-035
Abstract
In Helly-fixed cerebella, the toluidine blue – molybdate staining procedure reveals the existence of four distinct types of ribonucleoprotein in both the Purkinje cells of the vermian zone and the multipolar ganglion cells of the fastigial nucleus. These four types of ribonucleoprotein are found in, respectively, the ground substance (nucleolar matrix) of the nucleolus, the intranucleolar vacuoles (nucleolini), the intranuclear paranucleolar masses, and the cytoplasmic Nissl bodies. The relevant observational evidence suggests that the two organelles of the nucleolar apparatus, that is, the nucleolus and paranucleolar masses together with their associated chromocenters, are concerned with distinct synthetic activities with regard to the elaboration of neuronal ribonucleic acids or ribonucleoproteins. The significance of the above findings is discussed in the light of current concepts pertaining to cellular ribonucleoprotein metabolism.Keywords
This publication has 21 references indexed in Scilit:
- Axonal migration of proteins in the central nervous system and peripheral nerves as shown by radioautographyJournal of Comparative Neurology, 1963
- Cytochemical observations on the nucleolus-ribosome systemExperimental Cell Research, 1963
- PERCHLORIC ACID EXTRACTION AS A HISTOCHEMICAL TECHNIQUEJournal of Histochemistry & Cytochemistry, 1963
- Light and electron microscopic observations of an intranucleolar body in nerve cellsJournal of Ultrastructure Research, 1963
- THE BASE COMPOSITION OF NUCLEIC ACIDS IN CHROMOSOMES, PUFFS, NUCLEOLI, AND CYTOPLASM OF CHIRONOMUS SALIVARY GLAND CELLSThe Journal of cell biology, 1962
- Untersuchungen über morphologische Veränderungen in Spinalganglien während der retrograden DegenerationCell and tissue research, 1961
- Untersuchungen ber den Feinbau von SpinalganglienCell and tissue research, 1961
- ber den Nucleolus der NervenzelleCell and tissue research, 1953
- The morphology of the nerve cell nucleus, according to sexThe Anatomical Record, 1950
- A Morphological Distinction between Neurones of the Male and Female, and the Behaviour of the Nucleolar Satellite during Accelerated Nucleoprotein SynthesisNature, 1949