THE PATTERN OF ENZYME DISTRIBUTION IN THE BRAIN AND MENTAL FUNCTION

Abstract

The pattern of distribution of carbonic anhydrase in the central nervous system of man was given. The subcortical white matter had a greater amt. than the cortex except in the motor area. The occipital pole had the greatest amt., the temporal pole the least, with the frontal and parietal lobes intermediate. The variation of this pattern in a few cases of abnormal brains was cited, and a theory of mental dysfunction on the basis of alteration of the quantitative incidence of essential enzymes propounded.