Abstract
The embryohormonic relationship of the suprarenal cortex to mesothelial tissues is shown. For practical study the important tissues derived from the mesothelium are the striated muscle, including cardiac muscle, and the sex glands. Hypofunction of the suprarenal cortex as in Addison''s disease produces marked muscular asthenia, including asthenia of the heart muscle with low blood pressure and hypofunction of the sex glands. Hyperfunctionating tumors of the suprarenal cortex produce a precocious development of the sex glands and very marked increase in muscular strength. Primary pituitary disease produces secondary changes in the suprarenal cortex and the tissues under its control.

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