The Biosynthesis of Fumigatin.

Abstract
Fumigatin produced by a strain of Aspergillus fumigatus in presence of (A) C14-labelled sodium acetate, (b) Cl4H3-L-methionine, and (C) 2-Cl4-orsellinic acid was isolated and the distribution of radioactivity determined. It was shown that (A) fumigatin is biosynthesized in accordance with the acetate theory, (B) the methoxyl C of fumigatin is derived from the C1-pool, and (C) orsellinic acid is an intermediate in the biosynthesis of fumigatin.