Cardiac-specific troponin I levels and risk of coronary artery disease and graft failure following heart transplantation.

Abstract

The cardiac isoforms of troponins T and I have been used to evaluate myocardial cell damage associated with unstable angina and myocardial infarction or following cardiac surgery.^1-6 Measurements of the cardiac-specific contractile proteins troponins T and I are superior to conventional measurement of other enzymes, such as creatine kinase MB, for detecting minor myocardial injury^7,8 and are valid predictors of adverse events in patients with acute coronary syndromes.^2,9-14