Haemophilus ducreyiinfections – time for reappraisal
- 1 August 1982
- journal article
- research article
- Published by Cambridge University Press (CUP) in Epidemiology and Infection
- Vol. 89 (3), 467-478
- https://doi.org/10.1017/s0022172400071035
Abstract
Summary: As the literature onHaemophilus ducreyiand clinical chancroid is reviewed, it becomes obvious that many significant findings have been forgotten over the years. As a result, from the time of Ducrey's original description of the organism in 1890 until about 1977, both clinical and laboratory experts in the United Kingdom believed thatH. ducreyiinfections were rare, generally acquired abroad, and almost impossible to confirm in the routine laboratory! In consequence it was a common view that it was not worth looking forH. ducreyiuntil all other possible causes of genital ulceration had been excluded. Moreover, the search for such an infection stopped as soon as any other cause for the patient's lesions had been found.A decision to ignore this ‘rule’ in Sheffield led to our looking forH. ducreyiin specimens from an unselected series of patients with genital ulceration including a number with herpes genitalis infections. The surprise finding ofH. ducreyiin circumstances suggesting that it was a secondary invader made us re-examine the whole question ofH. ducreyiinfections and chancroid and wonder if the same organism can act as a primary pathogen and as a secondary invader. An account of the media and methods we used and of the characteristics of the organism is presented. In an attempt to find out more about the characteristic coherent colonies ofH. ducreyiwe studied them with the scanning electron microscope. It is clear that the whole subject ofH. ducreyiinfections has been neglected in the United Kingdom, but we believe that interest has now been aroused and progress will surely follow. Some areas for further investigation are suggested.This publication has 41 references indexed in Scilit:
- MODIFIED HAEMIN-CONTAINING MEDIUM FOR ISOLATION OF HAEMOPHILUS DUCREYIThe Lancet, 1982
- Chancroid in Sheffield. A report of 22 cases diagnosed by isolating Haemophilus ducreyi in a modified medium.Sexually Transmitted Infections, 1981
- Rising incidence of chancroid in Rotterdam. Epidemiological, clinical, diagnostic, and therapeutic aspects.Sexually Transmitted Infections, 1979
- A Taxonomic Study of the Genus Haemophilus, with the Proposal of a New SpeciesJournal of General Microbiology, 1976
- Simplified laboratory technique for diagnosis of chancroidArchives of Dermatology, 1970
- Treatment of chancroid. A comparison of tetracycline and sulfisoxazoleArchives of Dermatology, 1969
- V.D.R.L. Chancroid StudiesJournal of Investigative Dermatology, 1956
- V.D.R.L. Chancroid StudiesJournal of Investigative Dermatology, 1956
- Clinical and Laboratory Investigation of 370 Cases of ChancroidJournal of Investigative Dermatology, 1945
- Observations on chancroidal infectionThe Journal of Infectious Diseases, 1924