Effect of Cortisone in Sarcoidosis

Abstract

ALTHOUGH sarcoidosis is commonly considered a benign condition, it may occasionally be a serious illness, resulting in blindness, respiratory insufficiency or death. In a search for an effective therapeutic agent, many substances have been tried. Fowler's solution and x-ray therapy have been found ineffective.¹ More recently, benefit has been reported from the use of calciferol (vitamin D2),² nitrogen mustard,³ and urethane,⁴ but in our experience neither these agents nor antibiotics have given consistent results.Because it tends to involve many organs, sarcoidosis bears a clinical resemblance to certain of the disseminated collagen diseases. The hyperglobulinemia characteristic of sarcoidosis is also . . .