Electrolyte Excretion in Bile

Abstract

The high concentration of certain test substances in both urine and bile suggests that similarities exist between the biliary and renal tubular functions. Evidence from dogs with permanent duodenal fistulas indicates that the rate of elaboration of bile depends primarily on the rate of secretion of bile salts. The variations in flow and composition of hepatic bile seem to result from the addition of a fluid which is similar in some respects to pancreatic juice.