Our purpose in this paper is primarily to present in tabular form statistics on the metrazol and camphormetrazol irritative therapies obtained through the cooperation of seventy-five clinics. It is our further purpose to bring to the attention of the various workers in the more or less recently developed chemotherapeutic procedures certain important points regarding indications, contraindications, complications and technic and, finally, certain theoretical considerations of the modus operandi of convulsive-irritative therapy. STATISTICAL SECTION The case material shown in the tables was derived from direct correspondence with the hospitals and workers respectively listed. For the most part these tables are self explanatory. Because of the great variability in the statistical classification of the duration of illness by the various European workers, this feature was given in terms of less or more than one and one-half years. It was rather unfortunate in a sense that a more detailed analysis of the types