Asymmetric Synthesis. VII. Double Stereodifferentiation in Allylation of Ketimines Bearing Two Chiral Auxiliaries. Application to Enantioselective Synthesis of α-Allylglycine
- 1 March 1989
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 19 (5), 881-888
- https://doi.org/10.1080/00397918908051007
Abstract
A double asymmetric induction has been observed in allylation of the imines derived from (+)-camphor, (+)- and (-)- 2-hydroxypinan-3-ones with (+)- and (-)-menthyl glycinates. After hydrolysis of the allylated intermediates, (R)- and (S)-α-allylglycines are obtained in 3–90% optical yields.Keywords
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