Cases of coccidioidal granuloma are of increasing interest to those of us living in California. The disease was first described by Posadas1in Buenos Aires in 1900, the same case having been observed and reported independently by Wernicke2in 1892. Rixford,3in 1894, recognized the first case in California. This case with another observed by Thorne4was described later in greater detail by Rixford and Gilchrist,5who believed that the infecting organism was a protozoan belonging to the group ofCoccidia, and suggested the name ofCoccidioides immitisfor the organism. Ophüls and Moffit,6in 1900, observed another case and found that the parasite grew readily on artificial mediums and developed a mold. It apparently belonged to the group ofOidia. Ophüls7then gave the name ofOidium coccidioidesto the parasitic organism and coccidioidal granuloma to the lesion produced by it. It