Reproduction in a woman with low percentage t(21q21q) mosaicism.
- 1 June 1977
- journal article
- research article
- Published by BMJ in Journal of Medical Genetics
- Vol. 14 (3), 221-223
- https://doi.org/10.1136/jmg.14.3.221
Abstract
The birth of a child with Down syndrome followed by the conception of a fetus, both bearing the t(21q21q) chromosome in 100% of their cells, is described for a woman mosaic for the translocation in less than 10% of 2 of her examined tissues and in none of the cells in her peripheral blood. The importance of examining as many parental tissues as possible for the detection of low percentage mosaicism is stressed.This publication has 7 references indexed in Scilit:
- A family with three sibs carrying trisomy 21.1975
- Trisomy 21 mosaicism in a woman with two children with trisomy 21 Down's syndromeJournal of Medical Genetics, 1974
- Paternal trisomy 21 mosaicism and Down's syndrome.1971
- DOWN'S SYNDROME TRANSMITTED THROUGH MATERNAL MOSAICISMActa Paediatrica, 1969
- DE-NOVO G-G-TRANSLOCATION DOWN'S SYNDROME IN TWO SIBLINGSThe Lancet, 1969
- Familial mongolism by a G/G mosaic carrierThe Journal of Pediatrics, 1966
- TWO UNUSUAL CASES OF FAMILIAL MONGOLISMCanadian Journal of Genetics and Cytology, 1964