Induction of Glucagon Synthesis in Diabetic CBA Mice Bearing Mammary Aplastic Carcinomas
- 1 October 1979
- journal article
- research article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 63 (4), 1005-1008
- https://doi.org/10.1093/jnci/63.4.1005
Abstract
Passaging of the mammary aplastic carcinoma several times in diabetic CBA mice induced an extrapancreatic secretion of glucagon. Consequently, the concentration of immunoreactive glucagon was higher in plasma and the tumor tissue extract. After the injection of alloxan, attempts to reduce the level of this hormone in the diabetic mice were unsuccessful. The tumor cells could have been responsible for the secretion of glucagon.Keywords
This publication has 4 references indexed in Scilit:
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- GROWTH AND TREATMENT OF EHRLICH TUMOR IN MICE WITH ALLOXAN-INDUCED DIABETES1979
- Recovery of Immune System in Diabetic Mice after Treatment with InsulinHormone and Metabolic Research, 1978
- Growth of a thymoma in diabetic mice treated with insulinEuropean Journal of Cancer (1965), 1978