Unusual Ph1 Translocation in Acute Myeloblastic Leukemia

Abstract

To the Editor: A small number of Ph¹+ acute myeloblastic leukemias and an even smaller number of acute lymphoblastic leukemias have been described.¹ The Ph¹ in these cases is indistinguishable from that occurring in chronic myelocytic leukemia, in which, as a rule, the 22q-deleted material is translocated upon the long arm of chromosome No. 9.² In about 8 per cent of the cases of chronic myelocytic leukemia, however, the translocation is found on a chromosome other than No. 9.³ On the other hand, only cases of acute lymphoblastic and three of acute myeloblastic leukemia (one an erythroleukemia) have been . . .