Light-Induced Oxidative Stress in Choroidal Endothelial Cells in Mice

Abstract

Purpose. Although light-induced oxidative stress in the retina has been extensively reported, little information regarding light-induced oxidative stress in choroidal endothelial cells (CECs) is available. In the current study, light-induced DNA oxidation and the activation of nuclear factor-κB (NF-κB), a major oxidative responsive transcription factor, were investigated in mouse CECs.