THERE IS SUBSTANTIAL evidence that the teeth of prematurely born children are discolored as the result of tetracycline deposition therein during prophylactic or therapeutic regimens instituted after birth.1, 2 Detailed clinical studies of patients with cystic fibrosis of the pancreas3-5 and laboratory studies on animals dosed with tetracycline at various stages during their development have provided additional gross and microscopic evidence of discoloration of teeth induced by tetracycline. Also, much information has appeared in the literature describing the particular affinity and selectivity which tetracycline compounds exhibit for bone and tooth substances. This report describes the case of an infant with discolored deciduous teeth whose mother had received tetracycline during pregnancy. Since the preparation of this manuscript was undertaken two papers have been published which describe discoloration of the deciduous dentition of a child after tetracycline therapy to the mother during the period of gestation. In a brief note, Harcourt