Influence of Crude Trypsin Inhibitor on Utilization of Hydrolyzed Protein

Abstract

Addition of an extract of raw soybeans containing active trypsin inhibitor to diets containing either casein or an enzymatic protein hydrolysate (Protolysate) caused a decrease in growth rate and protein utilization of mice without affecting food intake. Autoclaving, which inactivated the trypsin inhibitor, abolished the harmful effects of the extract. It has been concluded that the deleterious effects resulting from the ingestion of an extract of raw soybeans are not necessarily due to an interference with the intestinal digestion of dietary protein.