A gradient of adhesive specificity in developing avian retina.

Abstract
Cell-cell adhesion was examined in the developing chick embryonic neural retina. A dorsoventral gradient of adhesive specificity in dissociated cells was detected which exhibits a complementarity such that the highest cell-cell affinities are exhibited between cells derived from the extremes of the gradient. If a nasotemporal gradient exists it must exhibit significantly lower cell-cell affinity. The relevance of these findings to pattern formation in the nervous system is discussed.

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