SUBMERGED CULTURE OF MAMMALIAN CELLS: THE FIVE LITER FERMENTOR,
- 1 December 1957
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 74 (6), 768-774
- https://doi.org/10.1128/jb.74.6.768-774.1957
Abstract
A variety of conditions is described under which the growth of "L" cells has been attained in a 5-1 fermentor which is a prototype of the antibiotic fermentors. A thorough evaluation of these conditions is contemplated. The growth exhibited in this type of equipment establishes the feasibility of growing mammalian cells on a large scale in submerged culture.Keywords
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