Magnesium in acute myocardial infarction

Abstract
Small trials reporting the use of magnesium in acute myocardial infarction have been reported intermittently for 20 years. The rationale for these studies came partly from observations of differences in heart attack rates associated with geographical variations in magnesium in the water supply and partly from laboratory studies showing that magnesium had cardioprotective effects during ischaemia and that myocardial magnesium concentrations were relatively low during acute ischaemia.1