Mechanisms of Rhythm Generation in a Spinal Locomotor Network Deprived of Crossed Connections: The Lamprey Hemicord
Open Access
- 26 January 2005
- journal article
- Published by Society for Neuroscience in Journal of Neuroscience
- Vol. 25 (4), 923-935
- https://doi.org/10.1523/jneurosci.2301-04.2005
Abstract
The spinal network coordinating locomotion in the lamprey serves as a model system, in which it has been possible to elucidate connectivity and cellular mechanisms using the isolated spinal cord. Locomotor burst activity alternates between the left and right side of a segment through reciprocal inhibition. We have recently shown that the burst generation itself in a hemisegment does not require inhibitory mechanisms. The focus of this study is the intrinsic operation of this hemisegmental burst-generating component of the locomotor network.Keywords
This publication has 56 references indexed in Scilit:
- A Direct Comparison of Whole Cell Patch and Sharp Electrodes by Simultaneous Recording From Single Spinal Neurons in Frog TadpolesJournal of Neurophysiology, 2004
- The motor infrastructure: from ion channels to neuronal networksNature Reviews Neuroscience, 2003
- Fast and Slow Locomotor Burst Generation in the Hemispinal Cord of the LampreyJournal of Neurophysiology, 2003
- Adenosine A1 receptors modulate high voltage‐activated Ca2+ currents and motor pattern generation in the Xenopus embryoThe Journal of Physiology, 2000
- Regulation of rhythmic movements by purinergic neurotransmitters in frog embryosNature, 1996
- Spinal pattern generationCurrent Opinion in Neurobiology, 1994
- Newly Identified 'Glutamate Interneurons' and Their Role in Locomotion in the Lamprey Spinal CordScience, 1987
- Tonic inhibition of a new type of spinal interneurone during fictive locomotion in the lampreyActa Physiologica Scandinavica, 1986
- Counts of axons in electron microscopic sections of ventral roots in lampreysJournal of Comparative Neurology, 1984
- Use of sucrose gap for recording postsynaptic population potentials evoked by single interneurones in spinal motoneuronesBrain Research, 1981