Chemical Correlations of α-Santonin with (+)-Junenol and Acolamone

Abstract

The chemical transformation of the acetoxy ketone (5), which has previously been obtained from α-santonin, to (+)-junenol (1) and acolamone (3) has been carried out. In addition, isojunenol (2) was also derived from 5 via the trisubstituted olefin (9) which was obtained as the main product from the α- and β-oriented mesylates (8 and 11) on treatment with NaI in HMPA.