1. The vagus in the elasmobranch, Scyllium canicula, is an afferent pathway from the stomach, spiral valve, and mesentery. 2. There are no afferent fibers passing through the first large sympathetic ganglion or from the liver and testis, stimulation of which produces either cardiac or respiratory inhibition. 3. Removal of the sympathetic ganglia or destruction of the spinal cord as high as the first vertebra fails to prevent elicitation of the inhibitory reflexes provided the visceral branches of the vagi remain intact. 4. Faradic stimulation of the central end of a visceral branch of the vagus at the stomach produces cardiac and respiratory inhibition.