Differentiation of Pathological Conditions by Visual Evaluation of Serum Protein Electrophoretic Patterns

Abstract

An agar gel electrophoretic technique has been applied to the analysis of human serums from normal and pathological cases. Separation of proteins on a microscope slide produced clear patterns which allowed direct comparison and differentiation of samples from various pathological conditions by visual inspection. Examples are presented which illustrate a correlation of protein patterns with pathological conditions. The procedure is rapid, inexpensive, and relatively simple for screening and monitoring serum protein patterns in health and disease.