Microbiological and Genotypic Analysis of Methicillin-Resistant Staphylococcus aureus Bacteremia
- 1 September 2008
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 52 (9), 3441-3443
- https://doi.org/10.1128/aac.00357-08
Abstract
In a recent landmark trial of bacteremia caused by methicillin-resistant Staphylococcus aureus (MRSA) isolates, vancomycin MICs were ≥1 μg/ml for only 16% of the isolates, and accessory gene regulator ( agr ) function as measured by delta-hemolysin activity was absent or reduced in only 28.1% of the isolates. This clinical study did not capture a population of MRSA isolates predictive of vancomycin treatment failure.This publication has 16 references indexed in Scilit:
- Community-associated Methicillin-resistantStaphylococcus aureusIsolates and Healthcare-Associated Infections1Emerging Infectious Diseases, 2007
- High-Dose Vancomycin Therapy for Methicillin-Resistant Staphylococcus aureus InfectionsArchives of Internal Medicine, 2006
- Daptomycin versus Standard Therapy for Bacteremia and Endocarditis Caused byStaphylococcus aureusNew England Journal of Medicine, 2006
- Persistent Bacteremia Due to Methicillin‐ResistantStaphylococcus aureusInfection Is Associated withagrDysfunction and Low‐Level In Vitro Resistance to Thrombin‐Induced Platelet Microbicidal ProteinThe Journal of Infectious Diseases, 2004
- Accessory Gene Regulator Group II Polymorphism in Methicillin-Resistant Staphylococcus aureus Is Predictive of Failure of Vancomycin TherapyClinical Infectious Diseases, 2004
- spa Typing Method for Discriminating among Staphylococcus aureus Isolates: Implications for Use of a Single Marker To Detect Genetic Micro- and MacrovariationJournal of Clinical Microbiology, 2004
- Comparison of Community- and Health Care–Associated Methicillin-Resistant Staphylococcus aureus InfectionJAMA, 2003
- Typing of Methicillin-Resistant Staphylococcus aureus in a University Hospital Setting by Using Novel Software for spa Repeat Determination and Database ManagementJournal of Clinical Microbiology, 2003
- Analysis of the Genetic Variability of Genes Encoding the RNA III-Activating Components Agr and TRAP in a Population of Staphylococcus aureus Strains Isolated from Cows with MastitisJournal of Clinical Microbiology, 2002
- Structural Comparison of Three Types of Staphylococcal Cassette Chromosome mec Integrated in the Chromosome in Methicillin-Resistant Staphylococcus aureusAntimicrobial Agents and Chemotherapy, 2001