Replication-selective virotherapy for cancer: Biological principles, risk management and future directions
Top Cited Papers
- 1 July 2001
- journal article
- review article
- Published by Springer Nature in Nature Medicine
- Vol. 7 (7), 781-787
- https://doi.org/10.1038/89901
Abstract
In the search for novel cancer therapies that can be used in conjunction with existing treatments, one promising area of research is the use of viral vectors and whole viruses. This review describes the underlying biological principles and current status of the field, outlines approaches for improving clinical effectiveness and discusses the unique safety and regulatory issues surrounding viral therapies.Keywords
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