Abstract
Thirty-five patients with deep brain tumors were submitted to transtumoral stereotactic impedance monitoring and serial biopsy. The direct examination of the biopsy samples confirmed the presumptive clinical and neuroradiological diagnosis in 25 patients but in 10 patients the histological diagnosis differed from the presumptive one. In this 2nd group the treatment was changed as a result of the histological findings. Stereotactic biopsy avoided the risks of blind management. The technique, the indications and the diagnostic advantages of stereotactic biopsy are reported with 2 illustrative cases.