EPIDERMAL CHANGES IN HEAT AND ELECTRICALLY INJURED PIG SKIN - A LIGHT MICROSCOPIC STUDY OF THE INFLUENCE OF HEAT-ENERGY INTENSITY AND ELECTRICAL-CURRENT FREQUENCY

Abstract

Pigs were exposed to heat of low and high temperature and electricity of various frequences. Comparable amounts of energy were transferred in all experiments. In lesions induced by heat of low temperature granularity and/or fibrillarity of the cytoplasm were present in the epidermal cells. Lesions induced by heat of high temperature had a similar appearance, but occasionally white necrosis, defects in the epithelium and light yellow material in stratum corneum were present. Lesions induced by 100,000 Hz alternating current were segmental but otherwise microscopically often indistinguishable from lesions produced via transfer of heat of low temperature. Lesions induced by 8000 Hz and 50 Hz alternating current were segmental. Vesicular nuclei, white necrosis and yellow, clumped keratin were present in most lesions. Anode areas in direct current induced lesions showed a shrunken epidermis. The cytoplasm of the epidermal cells were often eosinophilic and homogeneous, and the nuclei were small with condensed chromatin. Occasionally, empty nuclei were noted. Yellow, clumped keratin was present in all lesions. In cathode areas, epidermis was of varying thickness and white necrosis and vesicular nuclei were present. The pathogenesis of the individual morphological features is discussed based upon theoretical concepts and the difference in morphology of the various lesions encountered in the present study as well as in other studies in this series of experiments. Except for lesions produced via transfer of high frequency alternating current the morphology of electrical lesions is specific. An alleged torture instrument was able to produce lesions similar to those observed in the experimental studies.