The Intracellular Location of the Agent of Mouse Scrapie
- 1 February 1964
- journal article
- research article
- Published by Microbiology Society in Journal of General Microbiology
- Vol. 34 (2), 319-325
- https://doi.org/10.1099/00221287-34-2-319
Abstract
SUMMARY: Homogenates of brains from mice clinically affected with scrapie have been fractionated by differential centrifugation and equilibration in sucrose density gradients. Most of the infectivity was found in the heavy particulate fraction containing mitochondria and possibly lysosomes.Keywords
This publication has 2 references indexed in Scilit:
- ISOLATION OF NERVE ENDINGS FROM BRAIN - AN ELECTRON-MICROSCOPIC STUDY OF CELL FRAGMENTS DERIVED BY HOMOGENIZATION AND CENTRIFUGATION1962
- A STUDY OF FIXATION FOR ELECTRON MICROSCOPYThe Journal of Experimental Medicine, 1952