Mitochondrial poisons cause depletion of reduced glutathione in isolated hepatocytes
- 1 May 1992
- journal article
- Published by Elsevier in Archives of Biochemistry and Biophysics
- Vol. 295 (1), 132-136
- https://doi.org/10.1016/0003-9861(92)90498-l
Abstract
No abstract availableKeywords
This publication has 24 references indexed in Scilit:
- Effects of 1‐Methyl‐4‐Phenyl‐ 1,2,3,6‐Tetrahydropyridine and 1 ‐Methyl‐4‐Phenylpyridinium Ion on ATP Levels of Mouse Brain SynaptosomesJournal of Neurochemistry, 1990
- Biochemical mechanism of action of the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)Toxicology Letters, 1989
- MPTP and MPTP analogs induced cell death in cultured rat hepatocytes involving the formation of pyridinium metabolitesToxicology and Applied Pharmacology, 1988
- Fructose prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced ATP depletion and toxicity in isolated hepatocytesBiochemical and Biophysical Research Communications, 1988
- Increased efflux rather than oxidation is the mechanism of glutathione depletion by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)Biochemical and Biophysical Research Communications, 1987
- A Dopaminergic Cell Line Variant Resistant to the Neurotoxin 1‐Methyl‐4‐Phenyl‐1,2,3,6‐TetrahydropyridineJournal of Neurochemistry, 1987
- Idiopathic Parkinson's disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patientsNeuroscience Letters, 1986
- 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and 1-methyl-4-phenylpyridine (MPP+) cause rapid ATP depletion in isolated hepatocytesBiochemical and Biophysical Research Communications, 1986
- Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridineLife Sciences, 1985
- Parkinson's disease: A disorder due to nigral glutathione deficiency?Neuroscience Letters, 1982