Obesity and the Aging of the Human Adrenal Cortex
- 1 January 1966
- journal article
- research article
- Published by S. Karger AG in Gerontologia Clinica
- Vol. 8 (6), 370-376
- https://doi.org/10.1159/000244975
Abstract
Two groups of subjects (n = 46 and n = 98) were studied with respect to 17-KS (ketosteroid), and 17-OHCS (hydroxycorticosterone) excretion rates and obesity. The degree of obesity in these subjects was estimated by 3 separate methods. In each case the ratio 17-KS/ 17-OHCS was lower in obese individuals who were as little as 10-20 lb overweight This lower 17-KS/17-OHCS ratio in obese subjects represented a premature aging of the adrenal cortex, and this depressed ratio may have some deleterious physiological effects.Keywords
This publication has 5 references indexed in Scilit:
- The 17-ketosteroid/17-Hydroxycorticosteroid Ratio as a Useful Measure of the Physiological Age of the Human Adrenal CortexJournal of Gerontology, 1966
- Effect of Starvation on Adrenal Cortical Function in Obese SubjectsJournal of Clinical Endocrinology & Metabolism, 1964
- Importance of Body Characteristics in the Excretion of 17-Ketosteroids and 17-Ketogenic Steroids in ObesityNew England Journal of Medicine, 1964
- Adrenal Cortical Function in “Obesity with Pink Striae” in the Young AdultJournal of Clinical Endocrinology & Metabolism, 1963
- STUDIES OF ADRENOCORTICAL FUNCTION IN OBESITYJournal of Clinical Endocrinology & Metabolism, 1959