Necrotizing Toxoplasmic Encephalitis and Herpetic Pneumonia Complicating Treated Hodgkin's Disease

Abstract

DECREASED resistance to infection has frequently been described in patients with Hodgkin's disease,¹ and therapeutic agents commonly used, such as corticosteroids, alkylating agents and x-rays, are all known to interfere with the immune response. It is not surprising, therefore, that cases of multiple severe infections complicating Hodgkin's disease so treated have been reported in recent years. The present report describes a case in which extensive necrotizing toxoplasmic encephalitis presented as a space-occupying intracranial mass. Another unusual feature of the case was the presence of herpetic pneumonia.Case ReportA 27-year-old salesman (N.I.H. 02–89–30) was admitted to the Clinical Center for . . .