OBSERVATIONS ON THE BLOOD IODINE. I. THE BLOOD IODINE IN HEALTH, IN THYROID AND CARDIORENAL DISEASE, AND IN LEUKEMIA

Abstract

Using the Trevorrow and Fashena method, the blood 1% for 20 normal [male][male] in New York City averaged 5.9[gamma]% (range 3.8-8.67); 20 normal [female][female] averaged 6.8[gamma]% (range 3.5-10.4[gamma]). The normal range was arbitrarily set at 4.0 to 10.07%. Various thyroid disturbances and forms of nervous imbalance showed no correlation between the blood I2 level, serum cholesterol or basal metabolic rate within each group. The blood I2 was elevated (10.2-38.5[gamma]) in 14 cases of hyperthyroidism and normal (6.7-9.5[gamma]) in 6. The serum cholesterol was low or normal. In 8 cases of hypertensive vascular disease the blood I2 was low or low normal, 2.0 to 6.9[gamma]; avg., 4.4[gamma]. The serum cholesterol was normal or high even with high basal metabolic rates. These findings may aid in differentiating certain types of hypertensive vascular disease from hyperthyroidism. In other heart diseases, the blood I2 was low or normal, but the serum cholesterol and basal metabolic rate were normal. In 12 cases of myeloid leukemia, the blood I2 was low in 75%, normal in 25%. The range was 1.3 to 7.4[gamma]; the avg., 3.4[gamma]. In 17 lymphoid leukemia cases the I* level was normal in 59%, high in 41%. The range was 4.3 to 17.9[gamma]; the avg., 9.3[gamma]. Except for 2 cases, 2 groups did not overlap. Basal metabolic rates were high in both groups. No correlation exists between the blood I2 level and various other clinical features of leukemia.