TOXIC CIRRHOSIS OF THE LIVER

Abstract
Many chlorinated hydrocarbons have a toxic action on the liver. Of these, chloroform (CHC13) is the best known. Carbon tetrachloride (CC14) is closely related chemically to chloroform and likewise is a hepatic poison. Because of its noninflammable character and because it is an excellent solvent for fats and greases, it is extensively used in industry.1It has been introduced into the home as a fire extinguisher and a dry cleaner under the trade names of "Pyrene" and "Carbona." It is sometimes used by hairdressers as a dry shampoo. It has supplanted such inflammable liquids as naphtha and gasoline in many commercial dry cleaning plants. It is widely used in medicine as a vermifuge in the treatment of hookworm disease. Many cases of acute poisoning have now been recorded following the inhalation of the fumes of carbon tetrachloride.2This may produce only a slight dizziness or nausea,