Enzymes for chemical synthesis
Top Cited Papers
- 1 January 2001
- journal article
- review article
- Published by Springer Nature in Nature
- Vol. 409 (6817), 232-240
- https://doi.org/10.1038/35051706
Abstract
New catalytic synthetic methods in organic chemistry that satisfy increasingly stringent environmental constraints are in great demand by the pharmaceutical and chemical industries. In addition, novel catalytic procedures are necessary to produce the emerging classes of organic compounds that are becoming the targets of molecular and biomedical research. Enzyme-catalysed chemical transformations are now widely recognized as practical alternatives to traditional (non-biological) organic synthesis, and as convenient solutions to certain intractable synthetic problems.Keywords
This publication has 69 references indexed in Scilit:
- The Catalytic Pathway of Cytochrome P450cam at Atomic ResolutionScience, 2000
- Chemoenzymatic Synthesis of α-(1→3)-Gal(NAc)-Terminating Glycosides of Complex Tertiary Sugar AlcoholsJournal of the American Chemical Society, 1999
- Enhanced Inhibition of Human Anti-Gal Antibody Binding to Mammalian Cells by Synthetic α-Gal Epitope PolymersJournal of the American Chemical Society, 1999
- Designing enzymatic resolution of aminesChemical Communications, 1999
- Lipases: Interfacial Enzymes with Attractive ApplicationsAngewandte Chemie International Edition, 1998
- Recombinant Baker's Yeast as a Whole-Cell Catalyst for Asymmetric Baeyer−Villiger OxidationsJournal of the American Chemical Society, 1998
- Regio- and Stereoselectivity of Particulate Methane Monooxygenase from Methylococcus capsulatus (Bath)Journal of the American Chemical Society, 1997
- Enantioselective Epoxidation of ω-Bromo-2-methyl-1-alkenes Catalyzed by Chloroperoxidase. Effect of Chain Length on Selectivity and EfficiencyJournal of the American Chemical Society, 1997
- Toluene Dioxygenase-Mediated cis-Dihydroxylation of Aromatics in Enantioselective Synthesis. Asymmetric Total Syntheses of Pancratistatin and 7-Deoxypancratistatin, Promising Antitumor Agents1Journal of the American Chemical Society, 1996
- Enzymes in Organic Synthesis: Alteration of Reversible Reactions to Irreversible ProcessesSynlett, 1994